The Substance
If you follow the instructions, what could go wrong?A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Description: A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Genres: Drama, Horror, Science Fiction
Homepage: https://mubi.com/en/thesubstance
Budget: $17,500,000 | Revenue : $46,818,041
Runtime: 141 minutes
Strange Darling
Venom: The Last Dance
Alien: Romulus
Joker: Folie à Deux
Apocalypse Z: The Beginning of the End
Smile 2
Megalopolis
The Wild Robot
Deadpool & Wolverine
Terrifier 3
Demi Moore
Played Elisabeth
Margaret Qualley
Played Sue
Dennis Quaid
Played Harvey
Edward Hamilton-Clark
Played Fred
Gore Abrams
Played Oliver
Oscar Lesage
Played Troy
Christian Erickson
Played Man at Diner
Robin Greer
Played Male Nurse
Tom Morton
Played Doctor
Hugo Diego Garcia
Played Diego - Boyfriend
Daniel Knight
Played Casting Director
Jonathon Carley
Played Assistant Casting Director
Jiselle Henderkott
Played Girl Auditioning / New Year's Eve Show Dancer
Akil Wingate
Played TV Host
Vincent Colombe
Played Man in Suit #1 - Harvey's Office
Billy Bentley
Played Man in Suit #2
Lennard Ridsdale
Played Man in Suit #3
Jordan Ford Silver
Played Assistant Director - Pump It Up Show
Oscar Salem
Played 2nd Assistant Director - Pump It Up Show
Viviane Bossina
Played Sue's Assistant
Matthew Luret
Played Floor Runner
Jana Bittnerová
Played Maria
Olivier Raynal
Played Alan - 2nd Agent
Tiffany Hofstetter
Played Stylist
Nicolas Royer
Played Guy in the Elevator
Nathan Rippy
Played Assistant Director - New Year's Eve Show
Manon Arizmendi
Played Little Girl - New Year's Eve Show
Virginie Kotlinski
Played Mother - New Year's Eve Show
Brett Gillen
Played Director of Photography - New Year's Eve Show
Charlotte Marquardt
Played Screaming Woman
Léa Hengl
Played Screaming Woman
Gaëlle Raymond
Played Screaming Woman
Claire Lemaire
Played Screaming Woman
Lila Boughoufala
Played Screaming Woman
Aurélien Lorgnier
Played Screaming Man
Ivan Sellier
Played Screaming Man
Philip Schurer
Played Screaming Man
Christian Bourmier
Played Shareholder
Martin Graham
Played Shareholder
Christian Bordeleau
Played Shareholder
Patrick Hamel
Played Shareholder
Didier D'Hondt
Played Shareholder
Jacques-Yves Dorges
Played Shareholder
Jean-Claude Matthey
Played Shareholder
Olivier Jarcin
Played Shareholder
Jean-Luc Magneron
Played Shareholder
Charlotte Murray
Played Allison - Diner Waitress
Aaron Kahn
Played Greeting Person
Gabriela Arnon
Played Greeting Person
Nancy Josephson Lahoussine
Played Greeting Person
Andrew Eldridge
Played Greeting Person
Denise Powers
Played Greeting Person
Bryan Jones
Played Greeting Person
Adam Carage
Played Happy Birthday Person
Maria McClurg
Played Happy Birthday Person
Andrew Desmond
Played Happy Birthday Person
Rebecca Lafont
Played Happy Birthday Person
Laura Puech
Played Isabella
Ryan Chidester
Played Stagehand
Céline Vogt
Played Elisabeth (Young) - Walk of Fame
Yannick Guérin
Played Clumsy Burger Guy - Walk of Fame
Jean Miel
Played Worker Walk of Fame
Paul Descoings
Played Worker Walk of Fame
Benoit Lévêque
Played Worker Walk of Fame
Arthur Molinet
Played Cocktail Bartender
Manon Sachot
Played Cocktail Lounge Couple
Bastien Jorelle
Played Cocktail Lounge Couple
Kelly Hoarau
Played Female Assistant - Towel
Michel Juskiewicz
Played George - Harvey's Friend
Louise Greggory
Played Restaurant Waitress
Christophe Sartirano
Played Guy Looking at Sue
Florent Torres
Played Guy Looking at Sue
Romain Caldeira
Played Billboard Technician
Barthelemy Thomas
Played Billboard Technician
Axel Baille
Played Photographer
Ashley Lambert
Played Additional Voices (voice)
Ranjani Brow
Played Additional Voices (voice)
Chase Fein
Played Additional Voices (voice)
Shane Sweet
Played Additional Voices (voice)
William Calvert
Played Additional Voices (voice)
Michael Corbett
Played Additional Voices (voice)
Stephen Apostolina
Played Additional Voices (voice)
Yann Bean
Played The Substance (voice)
Audrey Alcide
Played Pump It Up Show Dancer
Jonathan Jenvrin
Played Pump It Up Show Dancer
Mimi Maury
Played Pump It Up Show Dancer
Amelye Solange
Played Pump It Up Show Dancer
Kévin Table
Played Pump It Up Show Dancer
Laura Boera
Played Sparkle Your Life Show Dancer
Cissy Duc
Played Sparkle Your Life Show Dancer
Sophie Mercier
Played Sparkle Your Life Show Dancer
Marie Valton
Played Sparkle Your Life Show Dancer
Katrina Budzynski
Played New Year's Eve Show Dancer
Alicia Maury
Played New Year's Eve Show Dancer
Megane Adamik
Played New Year's Eve Show Dancer
Annalisa Pagnotta
Played New Year's Eve Show Dancer
Maelle Dantigny
Played New Year's Eve Show Dancer
Aleksandra Fontaine Kedzierska
Played New Year's Eve Show Dancer
Pauline Sagetat
Played New Year's Eve Show Dancer
Agustina Fitzsimons
Played New Year's Eve Show Dancer
Elena Shcheglova
Played New Year's Eve Show Dancer
Eve Marchant
Played New Year's Eve Show Dancer
Lola Donati
Played New Year's Eve Show Dancer
Kate Matthews
Played New Year's Eve Show Dancer
Ophélie Jonard
Played New Year's Eve Show Dancer
Pauline Richard
Played New Year's Eve Show Dancer
Laureen Cappelliez
Played New Year's Eve Show Dancer
Daria Panchenko
Played New Year's Eve Show Dancer
Delphine Beaulieu
Played New Year's Eve Show Dancer
Victoria Brun
Played New Year's Eve Show Dancer
Cara Chapman
Played New Year's Eve Show Dancer
Katharine Matthews
Played New Year's Eve Show Dancer
Alexandra Faget
Played New Year's Eve Show Dancer
Clémence Juville
Played New Year's Eve Show Dancer
Margot L'Entete
Played New Year's Eve Show Dancer
Hillary Sukhonos
Played New Year's Eve Show Dancer
Matthew Géczy
Played Bob Haswell (uncredited)
Namory Bakayoko
Played Silhouette (uncredited)
Gregory Defleur
Played Happy Birthday Person (uncredited)
Coralie Fargeat
Played Elizabeth's Arm During Injection / Monstro Elisasue (some shots) (uncredited)
Backdrops
Posters
Logos
